WebJan 1, 2005 · Cystatin C (cys-C) is a low molecular mass protein that was initially known as inter alia γ-trace, post-γ-globulin, and gamma-CSF. The amino acid sequence of the single polypeptide chain of human cys-C was determined in 1981 [1]. The protein did not display any significant homology with the sequences of any protein at that time. WebSerum concentrations of cystatin C are almost totally dependent on glomerular filtration rate (GFR). A reduction in GFR causes a rise in the concentration of cystatin C. 1,2 Can be used as a confirmatory test for the diagnosis of chronic kidney disease (CKD) in patients with a decreased GFR as estimated from creatinine.
eGFR Calculator National Kidney Foundation
WebCystatin C, another biomarker for estimating the GFR, has less non-GFR variation related to age, sex, and race than serum creatinine. 7 We proposed the use of cystatin C in the … WebMay 12, 2024 · Conclusion: Serum cystatin C is the best biomarker for diagnosis of AKI in pediatric cirrhotics, especially with decompensation and SBP. eGFR calculated on serum cystatin C–based equations is more reliable than creatinine-based ones. What is Known: • Acute kidney injury (AKI) is a common complication in cirrhotic adults. the pro home buyers nc
Cystatin C – Implementation in clinical laboratory practice
WebNormal GFR varies according to age, sex, and body size; in young adults it is approximately 120 ml/min/1.73 m 2 and declines in normal individuals with age. However, a decrease in GFR may also be a marker of kidney … WebCystatin C inversely correlates with the glomerular filtration rate (GFR), that is, elevated levels of cystatin C indicate decreased GFR. Cystatin C may provide more accurate … WebMar 6, 2015 · Hepatitis (A, B, C, and autoimmune): Any inflammation of the liver that can result in liver damage. Hepatitis can have many causes, including viruses and … signature cards army pubs