Ftsh protease
WebFeb 6, 2024 · We find that ftsH interacts with diverse genes during growth and overlaps functionally with the other heat-shock protease-encoding genes hslVU, lon, and clpXP to promote survival during growth arrest. Systematic deletion of the heat-shock protease-encoding genes reveals that the proteases function hierarchically during growth arrest, … WebAug 5, 2024 · FtsH is a membrane-bound AAA+ protease, and its protease activity toward LpxC is regulated by essential membrane proteins LapB and YejM. However, the regulatory mechanisms are elusive.
Ftsh protease
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WebJan 1, 2012 · FtsH is a conserved AAA protease found in eubacteria, mitochondria and chloroplasts. As typical for AAA + proteases, bacterial FtsH forms barrel-shaped homo … WebThe FtsH protease complex is a membrane-localized ATP-dependent protease found in all oxygenic photoautotrophs . It has a well-characterized role in the degradation of damaged PSII subunits during photoinhibitory and oxidative stresses ( 12 ), and it has also been implicated in the degradation and remodeling of cytochrome b 6 f (cyt b 6 f ...
WebJun 14, 2016 · As PORs B and C colocalize with EX1 and are very close to PSII and the FtsH protease (Table S1, Fig. S2, and Fig. 2), Ex1-dependent signaling seems to take its origin in grana margins adjacent to where Chl is released during the disassembly of damaged PSII, and newly synthesized Chl is integrated into the reconstituted PSII. WebApr 27, 2012 · FtsH is an evolutionary conserved membrane-bound metalloprotease complex. While in most prokaryotes FtsH is encoded by a single gene, multiple FtsH genes are found in eukaryotes. Genetic and biochemical data suggest that the Arabidopsis chloroplast FtsH is a hetero-hexamer. This raises the question why photosynthetic …
WebDescription : Protein degradation.peptidase families.metallopeptidase activities.FtsH endopeptidase activities.FtsH mitochondrial protease complexes.FtsH4/11 component Gene families : OG_01_0001758 (Archaeplastida) Phylogenetic Tree(s): OG_01_0001758_tree , WebJan 1, 2013 · FtsH, a member of the AAA (ATPases associated with a variety of cellular activities) family of proteins, is an ATP-dependent protease of ∼71 kDa anchored to the inner membrane.
WebApr 10, 2024 · MeeF and MeeY copurify with proteins of the general secretory pathway, and in their absence the FtsH membrane protease is essential for viability. MeeF and MeeY are also required for efficient function of the Mn2+-dependent lipoteichoic acid synthase (LtaS), a membrane-localized enzyme with an extracytoplasmic active site. Thus, MeeF and …
WebJun 10, 2016 · A number of studies have characterized B. burgdorferi proteases, and these enzymes would be excellent targets for designer drugs to treat Lyme disease. 43–46 For example, a study has shown that B. burgdorferi persister cells upregulate a protease called ClpP, and this protease would be a logical target for designer drug therapy. 43 Another ... lama kerja obat adalahWebJan 1, 2013 · FtsH is a membrane-bound and ATP-dependent protease of Escherichia coli, known to degrade SecY, a membrane protein for protein translocation, and CII, a soluble … je promeusWebFeb 3, 2006 · 2CE7, 2CEA. PubMed Abstract: The ATP-dependent integral membrane protease FtsH is universally conserved in bacteria. Orthologs exist in chloroplasts and mitochondria, where in humans the loss of a close FtsH-homolog causes a form of spastic paraplegia. FtsH plays a crucial role in quality control by degrading unneeded or … lamakera nttWebNov 9, 2010 · FtsH is an ATP-dependent metalloprotease present as a hexameric heterocomplex in thylakoid membranes. Encoded in the Arabidopsis thaliana YELLOW … je promotion listWebEnter the email address you signed up with and we'll email you a reset link. lamakera timurWebAug 14, 2024 · Despite the pivotal role of thylakoid-embedded FtsH protease complexes in the selective degradation of PSII subunits during repair, little is known about the factors involved in regulating FtsH expression. Here we show using the cyanobacterium Synechocystis sp. PCC 6803 that the Psb29 subunit, ... lamakeraWebAug 26, 2005 · Double mutant combinations among the different FTSH genes in Arabidopsis thaliana suggest that the duplicated genes are redundant and reveal that the presence of two types of subunits is essential for complex formation, photosystem II repair, and chloroplast biogenesis. FtsH protease is important in chloroplast biogenesis and … lama kerja dalam bahasa inggris